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Run too fast, NAD+ causes chest tightness, nausea, and a hot burning sensation

In HF patients, reduced m has been associated with accumulation of plasma long-chain acylcarnitines and impaired myocardial ATP synthesis

Taupin and Gage, 2002

Biochimie 158:7381 Chen P, Smith TJ, Wu J, Siesser PF, Bisnett BJ, Khan F et al (2017) Glycosylation of Keap1 links nutrient sensing to redox stress signaling